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Increased sensitivity to gemcitabine following Bcl-xL antisense treatment in pancreatic cancer cells

✍ Scribed by Xu, Zhongwei; Friess, Helmut; Aebi, Stefan; Korc, Murray; Kleeff, Jorg H.; Buchler, Markus W.

Book ID
123186446
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
166 KB
Volume
118
Category
Article
ISSN
0016-5085

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Pancreatic cancer is one of the leading causes of cancerrelated death in Western countries. Bcl-x L is an anti-apoptotic factor of the Bcl-2 family, which is overexpressed in pancreatic cancer and its presence correlates with shorter patient survival. In this study, sequence-specific antisense oligo