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BCL-XL depletion sensitizes pancreatic cancer cells to ligand-mediated apoptosis

✍ Scribed by BAI, J; DEMIRJIAN, A; VOLLMERJR, C; CALLERY, M


Book ID
123354945
Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
51 KB
Volume
9
Category
Article
ISSN
1091-255X

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Pancreatic cancer is one of the leading causes of cancerrelated death in Western countries. Bcl-x L is an anti-apoptotic factor of the Bcl-2 family, which is overexpressed in pancreatic cancer and its presence correlates with shorter patient survival. In this study, sequence-specific antisense oligo