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Bcl-XL depletion promotes apoptosis and retards growth of pancreatic cancer tumor xenografts

✍ Scribed by A.N. Demirjian; J. Bai; M.P. Callery


Book ID
116702039
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
78 KB
Volume
130
Category
Article
ISSN
0022-4804

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Pancreatic cancer is one of the leading causes of cancerrelated death in Western countries. Bcl-x L is an anti-apoptotic factor of the Bcl-2 family, which is overexpressed in pancreatic cancer and its presence correlates with shorter patient survival. In this study, sequence-specific antisense oligo