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BCL-2 AND BCL-XL ANTISENSE OLIGONUCLEOTIDES ENHANCE CYTOTOXICITY OF GEMCITABINE IN BLADDER CANCER CELL LINES

✍ Scribed by A. Becker; C. Bolenz; A. Schaaf; L. Trojan; Y. Cao; P. Alken; M.S. Michel


Book ID
118647379
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
58 KB
Volume
5
Category
Article
ISSN
1569-9056

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Pancreatic cancer is one of the leading causes of cancerrelated death in Western countries. Bcl-x L is an anti-apoptotic factor of the Bcl-2 family, which is overexpressed in pancreatic cancer and its presence correlates with shorter patient survival. In this study, sequence-specific antisense oligo