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Increased gene expression of matrix metalloproteinase-3 (stromelysin) in skin fibroblasts from patients with severe recessive dystrophic epidermolysis bullosa

โœ Scribed by Daisuke Sawamura; Takamitsu Sugawara; Isao Hashimoto; Leena Bruckner-Tuderman; Daisaburo Fujimoto; Yasunori Okada; Nobuo Utsumi; Hideo Shikata


Book ID
115764364
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
742 KB
Volume
174
Category
Article
ISSN
0006-291X

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Expression of collagenase and stromelysi
โœ T. Sato; K. Nomura; I. Hashimoto ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 970 KB

Collagenase and stromelysin expression in recessive dystrophic epidermolysis bullosa (RDEB) was studied at both the protein and the gene expression levels in fibroblast cultures. The amount of enzyme protein in the culture medium, as determined using a specific enzyme assay, showed a 9.7-fold increa