Increased frequency of a mutation in coagulation factor V associated with resistance to activated protein C in patients with coronary artery disease
✍ Scribed by M. Chen; H. Seydewitz; B. Winckelmann; M. Nauck; H. Wieland; L. Witt; W. März
- Book ID
- 118325992
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 105 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0021-9150
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The aim of our study was to determine the prevalence of the factor V mutation (position 1691 G->A) in patients with angiographically diagnosed coronary artery disease and myocardial infarction and, as a control, in blood donors. This mutation has already been proved to be the main genetic risk facto
## Background: Activated protein c (apc) resistance is the most frequently diagnosed heritable thrombophilic defect predisposing to thrombosis. ## Objectives: To determine the prevalence of apc resistance due to factor v leiden mutation in patients with leg ulcers. ## Methods: Within a 2-year-p