Increased bioavailability of cimetidine with age?
β Scribed by A. Somogyi; R. Gugler; A. Redolfi; E. Borgogelli; E. Lodola
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 330 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0031-6970
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π SIMILAR VOLUMES
Elevations in quinidine steady-state serum concentrations have been re orted in patients who received cimetidine concurrently."' Studies in normal volunteers3' have shown that areas under the serum concentration-time curve of orally administered quinidine are higher when quinidine is given during ch
A two-way crossover bioavailability study of two commercial cimetidine formulations was performed on 24 healthy male volunteers. Drug was administered after an overnight fast and plasma samples were withdrawn periodically for 12 h. Urine was collected throughout the study period. Results indicated t