✦ LIBER ✦

The effect of mannitol on the oral bioavailability of cimetidine

✍ Scribed by Dawn A. Adkin; Stanley S. Davis; Robert A. Sparrow; Paul D. Huckle; Ian R. Wilding

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 592 KB
Volume: 84
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600841205

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of cimetidine on quinidine bioava

Effect of cimetidine on quinidine bioavailability

✍ Janis J. Mackichan; Harisios Boudoulas; Stephen F. Schaal 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 280 KB 👁 2 views

Elevations in quinidine steady-state serum concentrations have been re orted in patients who received cimetidine concurrently."' Studies in normal volunteers3' have shown that areas under the serum concentration-time curve of orally administered quinidine are higher when quinidine is given during ch

Linezolid absolute bioavailability and t

Linezolid absolute bioavailability and the effect of food on oral bioavailability

✍ Ian R. Welshman; Theresa A. Sisson; Gail L. Jungbluth; Dennis J. Stalker; Nancy 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 1 views

Effect of fruit juices on the oral bioav

Effect of fruit juices on the oral bioavailability of fexofenadine in rats

✍ Amrita V. Kamath; Ming Yao; Yueping Zhang; Saeho Chong 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB 👁 1 views

Fexofenadine has been identified as a substrate for both the efflux transporter, P-glycoprotein (P-gp), as well as the influx transporter, organic anion transporting polypeptide (OATP). Clinical studies in humans showed that fruit juices reduced the oral bioavailability of fexofenadine by preferenti

The bioavailability of oral nitroglyceri

The bioavailability of oral nitroglycerin

✍ Patrick K. Noonan; Leslie Z. Benet 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

The effect of ciprofloxacin and clarithr

The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers

✍ Mohsen A. Hedaya; Dalia R. El-Afify; Gamal M. El-Maghraby 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

Sildenafil is the first oral therapeutic agent for the management of male erectile dysfunction. Its oral bioavailability is only 40% due to extensive presystemic elimination, mainly by CYP3A4. This study examined the effect of coadministration of ciprofloxacin or clarithromycin, which inhibit CYP3A4

The effects of chronic oral diltiazem an

The effects of chronic oral diltiazem and cimetidine dosing on the pharmacokinetics and negative dromotropic action of intravenous and oral diltiazem in the dog

✍ Chaiyasit Maskasame; Susan Lankford; Stephen A. Bai 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 953 KB

The kinetics and negative dromotropic action of intravenous (1 mg kg-') and oral (5 mg kg-') diltiazem were studied in dogs after acute doses, after treatment for 3 days with oral diltiazem (5 mg kg-I, t.i.d.), and after 3 days' treatment with oral diltiazem (5 mg kg-' t.i.d.) and cimetidine (200mg