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Increased Activity of c-Src and Csk in Fibroblasts Transformed by v-src Oncogene

✍ Scribed by Zdena Tuháčková; Martina Vojtěchová; Jan Hlaváček; Maria Ruzzene; Vlasta Sovová; Lorenzo A. Pinna


Book ID
115589286
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
88 KB
Volume
290
Category
Article
ISSN
0006-291X

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v-src±transformed fibroblasts have significantly reduced levels of gap junction±mediated intercellular communication. This observed downregulation of cellular communication has been associated with tyrosine phosphorylation of the gapjunction protein connexin 43 (Cx43). Previously, we demonstrated th