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SWAP-70 is required for oncogenic transformation by v-Src in mouse embryo fibroblasts

✍ Scribed by Yasuhisa Fukui; Takayuki Tanaka; Hiroyuki Tachikawa; Sayoko Ihara


Book ID
116294617
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
644 KB
Volume
356
Category
Article
ISSN
0006-291X

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## Abstract SWAP‐70 is a protein involved in actin rearrangement, especially in membrane ruffling. Mouse embryo fibroblasts (MEFs) deficient in SWAP‐70 show impaired membrane ruffling and fail to grow in soft agar after transformation by v‐Src. Here, we show that v‐Src transformed MEFs expressing S

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