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Increased 3-nitrotyrosine in brains of Apo E-deficient mice

✍ Scribed by Russell T. Matthews; M. Flint Beal

Book ID: 113128239
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 293 KB
Volume: 718
Category: Article
ISSN: 0006-8993
DOI: 10.1016/0006-8993(95)01576-0

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Apolipoprotein E (ApoE) is the major brain lipoprotein and plays an important role in lipid transport. ApoE-deficient mice whose apoE gene has been knocked out have distinct cognitive and neurochemical deficits, and their recovery from brain injury is impaired. In the present study we examined the p