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Abnormal development and increased 3-nitrotyrosine in copper-deficient mouse embryos

✍ Scribed by Molly E. Beckers-Trapp; Louise Lanoue; Carl L. Keen; Robert B. Rucker; Janet Y. Uriu-Adams

Book ID: 113629704
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 306 KB
Volume: 40
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2005.08.020

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Rat embryos (gestation days 9.0 and 10.0) obtained from dams that were fed a Cu-adequate (8 micrograms Cu/g) or Cu-deficient (< 0.5 micrograms Cu/g diet were cultured for 48 hr in Cu-adequate (16.2 microM) or Cu-deficient (1.0 microM) rat serum. Control embryos cultured in control serum were morphol