## Abstract Mice lacking JIP1, a scaffold protein that organizes JNK pathway components, were constructed independently by two groups. The proposed in vivo function, however, remains contradictory; One study reported that targeted disruption of the __jip1__ caused embryonic death due to the require
✦ LIBER ✦
Deficiency of Myeloperoxidase Increases Infarct Volume and Nitrotyrosine Formation in Mouse Brain
✍ Scribed by Takizawa, Shunya; Aratani, Yasuaki; Fukuyama, Naoto; Maeda, Nobuyo; Hirabayashi, Hisayuki; Koyama, Hideki; Shinohara, Yukito; Nakazawa, Hiroe
- Book ID
- 110079157
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 256 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0271-678X
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## Abstract Semaphorins, a family of secreted and membrane‐bound proteins, are known to function as repulsive axon guidance molecules. Sema4D, a class 4 transmembrane‐type semaphorin, is expressed by oligodendrocytes in the central nervous system, but its role is unknown. In this study, the effects