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Inclusion of New Microsatellite Repeats in Allelic Loss Analysis Excludes Retention of Heterozygosity in the Renal Cell Carcinoma Critical Region in 3p21

✍ Scribed by Klaas Kok; Tineke G Draaijers; Albert Mosselaar; Debora de Jong; Charles H.C.M Buys


Book ID
114136964
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
135 KB
Volume
116
Category
Article
ISSN
0165-4608

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In a loss of heterozygosity analysis of 3p, we examined 44 sporadic cases of renal cell carcinoma (RCC) and matched normal tissue with 18 markers distributed over the whole p-arm. The majority of these markers clustered in three regions that have been suggested t o be involved in the development of