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Incidence of diabetes mellitus among children of Italian migrants substantiates the role of genetic factors in the pathogenesis of type 1 diabetes

✍ Scribed by Stefan Ehehalt; Pavle Popovic; Sergio Muntoni; Sandro Muntoni; Andre Willasch; Regine Hub; Michael B. Ranke; Andreas Neu; for the DIARY Group Baden-Wuerttemberg

Publisher
Springer
Year
2008
Tongue
English
Weight
126 KB
Volume
168
Category
Article
ISSN
0340-6997

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Over 30 years after the original description of Randle's cycle, the mechanisms by which elevated circulating non-esterified fatty acids might be causally related to glucose intolerance in Type 2 diabetes mellitus remain uncertain. This review examines the evidence that elevated plasma NEFA can inhib