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In Vivo Suppression of Precore mRNA Synthesis Is Associated with Mutations in the Hepatitis B Virus Core Promoter

✍ Scribed by Andreas Laras; John Koskinas; Stephanos J. Hadziyannis

Book ID
112273961
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
225 KB
Volume
295
Category
Article
ISSN
0042-6822

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Mutations in the core promoter and precore regions are frequently found in hepatitis B e antigen (HBeAg)-negative patients, but precore stop codon mutation is restricted to hepatitis B virus (HBV) genotypes that have T at nucleotide 1858. The aims of this study were to determine the role of core pro