The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer
Prevalence of Mutations in Core Promoter/Precore Region in Japanese Patients with Chronic Hepatitis B Virus Infection
โ Scribed by Atsushi Nagasaka; Shuhei Hige; Masumi Marutani; Izumi Tsunematsu; Makoto Saito; Yoshiya Yamamoto; Shigeru Konishi; Masahiro Asaka
- Book ID
- 111567395
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 136 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0163-2116
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To investigate the meaning of the mutations in the enhancer 2/core promoter (Enh2/CP) region of hepatitis B virus (HBV) during the chronic HBV infection, mutations were examined in the Enh2/ CP region (carboxyl half of X region) and their correlation with mutations in the precore and core regions in