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In vivo study of nmda-sensitive glutamate receptor by fluorothienylcycloexylpiperidine, a possible ligand for positron emission tomography

✍ Scribed by C. Ferrarese; A. Guidotti; E. Costa; R.S. Miletich; K.C. Rice; B.R. de Costa; M.J. Fulham; G. Di Chiro

Book ID
118956451
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
805 KB
Volume
30
Category
Article
ISSN
0028-3908

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## Abstract Iodobenzamide (IMB) labeled with either [^11^C] or [^125^I] was studied in mice and baboons. Pharmacological studies demonstrated an in vivo binding profile compatible with D~2~ dopamine receptors. Mouse biodistribution studies with both [^11^C]IMB and [^125^I]IMB showed a similar brain