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Synthesis of [11C]granisetron, a possible positron emission tomography ligand for 5-HT3 receptor studies

โœ Scribed by I. Vandersteene; K. Audenaert; G. Slegers; R. Dierckx


Publisher
John Wiley and Sons
Year
1998
Tongue
French
Weight
413 KB
Volume
41
Category
Article
ISSN
0022-2135

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Synthesis of [11C]-S21007 a novel 5HT3 p
โœ S. Guillouet; L. Barre; F. Gourand; M. C. Lasne; S. Rault ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 187 KB

A novel selective and partial agonist S21007 (IC% =InM), for 5HT3 receptor studies in positron emission tomography, has been labelled with ("Cjbenzyl iodide in 40-50% radiochemical yield and 200-700mCilpmol in 60 min synthesis time.