Synthesis of [11C]-S21007 a novel 5HT3 partial agonist as a potential tracer for PET studies

✍ Scribed by S. Guillouet; L. Barre; F. Gourand; M. C. Lasne; S. Rault

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: French
• Weight: 187 KB
• Volume: 38
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/(sici)1099-1344(199604)38:4<367::aid-jlcr846>3.0.co;2-n

✦ Synopsis

A novel selective and partial agonist S21007 (IC% =InM), for 5HT3 receptor studies in positron emission tomography, has been labelled with ("Cjbenzyl iodide in 40-50% radiochemical yield and 200-700mCilpmol in 60 min synthesis time.