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In vivo Retrovirus-mediated Herpes Simplex Virus Thymidine Kinase Gene Therapy Approach for Adult T Cell Leukemia in a Rat Model

✍ Scribed by Murata, Ken ;Fujita, Masatoshi ;Yamada, Yasuaki ;Higami, Yoshikazu ;Shimokawa, Isao ;Tsukasaki, Kunihiro ;Tanaka, Yuetsu ;Maeda, Michiyuki ;Furukawa, Koichi ;Yoshiki, Takashi ;Shiku, Hiroshi ;Tomonaga, Masao


Book ID
108581439
Publisher
Wiley (Blackwell Publishing)
Year
1997
Tongue
English
Weight
530 KB
Volume
88
Category
Article
ISSN
0910-5050

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Retrovirus-mediated transfer of the herp
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Currently, there is no effective treatment for pancreatic cancer and prodrug-activating gene therapy with the herpes simplex virus thymidine kinase gene (HSV-tk) in combination with ganciclovir (GCV) has been suggested as a candidate approach against this disease. In the present study, we have evalu