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In vivo imaging of muscarinic receptors in the aging female brain with (R,R)[123I]-I-QNB and single photon emission tomography

✍ Scribed by R. Norbury; M.J. Travis; K. Erlandsson; W. Waddington; J. Owens; S. Pimlott; P.J. Ell; D.G.M. Murphy

Book ID
113614585
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
192 KB
Volume
40
Category
Article
ISSN
0531-5565

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## Abstract The high‐affinity muscarinic receptor antagonist (R,R) I‐QNB^(1)^ [(R)‐(‐)‐1‐Azabicyclo [2.2.2]oct‐3‐yl‐ (R) ‐ (+) ‐ α‐hydroxy‐α‐(4‐[^127^I]iodophenyl)‐α‐phenyl Acetate (6a)] has been labeled with iodine‐123 to give a suitable ligand for SPECT (Single photon emission computed tomography