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In vivo and in vitro evidence that cross-reactive antibodies to C-terminus of hypervariable region 1 do not neutralize heterologous hepatitis C virus

✍ Scribed by Mariko Esumi; Yi-Hua Zhou; Tetsuya Tanoue; Tetsushi Tomoguri; Ikuo Hayasaka

Book ID
117431044
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
232 KB
Volume
20
Category
Article
ISSN
0264-410X

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## Abstract Hepatitis C virus (HCV) infection may result in acute resolving or chronic infection. Patients that clear the infection have a more vigorous cellular immune response and an early humoral response to the hypervariable region 1 (HVR1) of the E2 envelope protein. To analyse further the pro