Islet cell lines were produced by retroviral transduction of SV-40 T antigen to monolayer cultures of neonatal rat islets. One line, RN0-11, showed evolution of phenotypes in vitro. It evolved from a non-hormone secreting cell line to an insulin secreting line. It further developed glucagon producin
In vivo and in vitro development of mouse pancreatic β-cells in organotypic slices
✍ Scribed by Tiziana Meneghel-Rozzo; Aldo Rozzo; Lisa Poppi; Marjan Rupnik
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 526 KB
- Volume
- 316
- Category
- Article
- ISSN
- 0302-766X
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