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Telomerase-specific T-cells kill pancreatic tumor cells in vitro and in vivo

✍ Scribed by Jan Schmidt; Eduard Ryschich; Elisabeth Sievers; Ingo G. H. Schmidt-Wolf; Markus W. Büchler; Angela Märten


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
159 KB
Volume
106
Category
Article
ISSN
0008-543X

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## Abstract Valproic acid (VA) is a well‐tolerated drug used to treat seizure disorders and has recently been shown to inhibit histone deacetylase (HDAC). Because HDAC modulates chromatin structure and gene expression, parameters considered to influence radioresponse, we investigated the effects of