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In vivo adenovirus-mediated gene transfer and expression in ischemic rabbit spinal cord

โœ Scribed by Sakurai, Masahiro; Abe, Koji; Hayashi, Takeshi; Warita, Hitoshi; Setoguchi, Yasuhiro; Itoyama, Yasuto; Tabayashi, Koichi


Book ID
122191951
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
473 KB
Volume
30
Category
Article
ISSN
1097-6809

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We used recombinant adenoviruses as a means of expressing exogenous genes in olfactory neurons in vivo. A replication incompetent adenovirus (type 5, Ad5) carrying the reporter gene lacZ, which codes for the enzyme 8-galactosidase (,&Gal), was applied in solution to the olfactory epithelia of rats.