In vitro tumor necrosis factor cytotoxic
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Daniell B. Hill; Jack Schmidt; Steven I. Shedlofsky; Donald A. Cohen; Craig J. M
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Article
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1995
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John Wiley and Sons
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English
β 714 KB
Tumor necrosis factor-rY(TNF-a) is a mediator of liver injury. The objective of this study was to develop an in vitro model of TNF-mediated liver cell injury using the Hep G2 cell line. Hep G2 cells normally are insensitive to TNF' cytotoxicity, but they were rendered susceptible, or sensitized, to