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Tauroursodeoxycholic acid and ursodeoxycholic acid reduce ethanol cytotoxicity in vitro, in Hep G2 cells


Book ID
118566765
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
122 KB
Volume
21
Category
Article
ISSN
0168-8278

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Tumor necrosis factor-rY(TNF-a) is a mediator of liver injury. The objective of this study was to develop an in vitro model of TNF-mediated liver cell injury using the Hep G2 cell line. Hep G2 cells normally are insensitive to TNF' cytotoxicity, but they were rendered susceptible, or sensitized, to