Ribozymes are RNA molecules capable of catalyzing chemical reactions. Natural ribozymes generally accelerate the rate of cleavage and ligation of specific phosphodiester bonds. In vitro selection of RNA is now being used as a powerful technique to isolate novel and variant ribozymes that carry out c
β¦ LIBER β¦
In vitro selection of hairpin ribozymes
β Scribed by Alfredo Berzal-Herranz
- Book ID
- 118567483
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 129 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
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## Abstract Electrochemical impedance spectroscopy is successfully utilized for labelβfree monitoring of the cleavage reaction of a RNA substrate by a complementary hairpin ribozyme. The formation of the RNA substrate/ribozyme complex is increasing the negative charge at the interface and is modula