Engineering of Pichia pastoris for impro
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Brigitte Gasser; Michael Maurer; Johannes Gach; Renate Kunert; Diethard Mattanov
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Article
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2006
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John Wiley and Sons
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English
β 255 KB
π 1 views
## Abstract The methylotrophic yeast __Pichia pastoris__ has been used for the expression of many proteins, including antibody fragments. However, limitations became obvious especially when secreting heterodimeric Fab fragments. Upβtoβdate, antibody fragments have only been expressed under control