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In Vitro Porphobilinogen and Porphyrin Synthesis in Thalassemia Major and Sickle Cell Anemia

✍ Scribed by Felix Feldman; Herbert C. Lichtman

Book ID: 114877665
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 340 KB
Volume: 119
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1965.tb54054.x

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## Abstract The in vitro synthesis of hemoglobin chains was investigated in 34 scikle cell anemia (SS) patients and five patients with Hb S‐β^o^‐thalassemia. Incubations were made for 30 minutes and for 120 minutes. Hematological and family data were also obtained. Although the 30‐minute α/non‐α to