✦ LIBER ✦

Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major

✍ Scribed by Dr. Gary M. Brittenham; Alan R. Cohen; Christine E. McLaren; Marie B. Martin; Patricia M. Griffith; Arthur W. Nienhuis; Neal S. Young; Christopher J. Allen; David E. Farrell; John W. Harris

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 503 KB
Volume: 42
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.2830420116

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Patterns of hepatic iron distribution in

Patterns of hepatic iron distribution in patients with chronically transfused thalassemia and sickle cell disease

✍ Nilesh R. Ghugre; Ignacio Gonzalez-Gomez; Ellen Butensky; Leila Noetzli; Roland 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 190 KB 👁 2 views

## Abstract Patients with sickle cell disease (SCD) appear to be at lower risk of endocrinopathies and cardiac dysfunction than those with thalassemia major (TM). Circulating redox active iron is lower in these patients, possibly due to increased systemic inflammation and circulating cytokines. Hep

Spleen R2 and R2* in iron-overloaded pat

Spleen R2 and R2* in iron-overloaded patients with sickle cell disease and thalassemia major

✍ Casey J. Brewer; Thomas D. Coates; John C. Wood 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB

## Abstract ## Purpose To evaluate the magnetic properties of the spleen in chronically transfused, iron‐overloaded patients with sickle cell disease (SCD) and thalassemia major (TM) and to compare splenic iron burdens to those in the liver, heart, pancreas, and kidneys. ## Materials and Methods

Microarray analysis of liver gene expres

Microarray analysis of liver gene expression in iron overloaded patients with sickle cell anemia and beta-thalassemia

✍ Jonathan M. Flanagan; Shirley Steward; Jane S. Hankins; Thad M. Howard; Geoffrey 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB 👁 2 views

Cardiovascular function during rest and

Cardiovascular function during rest and exercise in patients with sickle-cell anemia and coexisting alpha thalassemia-2

✍ Braden, David S.; Covitz, Wesley; Milner, Paul F. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 595 KB

Cardiac function was measured at rest and during exercise in 9 patients with sickle-cell anemia (SS) and coexisting homozygous alpha thalassemia-2 (alpha thal-2). Results were compared with 18 sickle cell patients with normal alpha globin genes, who were matched to the study group by age, gender, an

Immune regulation in chronically transfu

Immune regulation in chronically transfused allo-antibody responder and nonresponder patients with sickle cell disease and β-thalassemia major

✍ Weili Bao; Hui Zhong; Xiaojuan Li; Margaret T. Lee; Joseph Schwartz; Sujit Sheth 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 661 KB

Influence of α-thalassemia trait on sple

Influence of α-thalassemia trait on spleen function in sickle cell anemia patients with high HbF

✍ Adekile, A.D.; Tuli, M.; Haider, M.Z.; Al-Zaabi, K.; Mohannadi, S.; Owunwanne, A 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 614 KB

Spleen function was studied in a group of 20 Kuwaiti SS patients (aged 2-12 years), using 99mTc-labeled tin colloid scintigraphy. They were screened for the alpha-thalassemia determinants which are prevalent in the Arabian Peninsula [-alpha (3.7 kb) deletion, alpha2-globin gene polyadenylation signa