## Abstract The most devastating complication of sickle cell anemia is cerebral infarction, affecting βΌ30% of all individuals with sickle cell anemia. Despite being one of the most common causes of stroke in infants and children, the mechanism of cerebral infarction in this population has not been
Alpha thalassemia and stroke risk in sickle cell anemia
β Scribed by Dr. Robert J. Adams; Abdullah Kutlar; Virgil McKie; Elizabeth Carl; Fenwick T. Nichols; Jin Cal Liu; Kathleen McKie; Anthony Clary
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 387 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0361-8609
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Cardiac function was measured at rest and during exercise in 9 patients with sickle-cell anemia (SS) and coexisting homozygous alpha thalassemia-2 (alpha thal-2). Results were compared with 18 sickle cell patients with normal alpha globin genes, who were matched to the study group by age, gender, an
## Abstract The diseases commonly confused with sickle cell anemia include sickle cellΞ²βthalassemia in which synthesis of Ξ²^A^βchains are completely suppressed (HbSβΞ²^O^βthalassemia). We obtained hematologic measurements and studied globin biosynthesis in five patients with this disorder and compar