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In Vitro Myotoxicity of Selected Cationic Macromolecules Used in Non-Viral Gene Delivery

✍ Scribed by Gayle A. Brazeau; Steve Attia; Scott Poxon; Jeffrey A. Hughes

Book ID: 110307835
Publisher: Springer US
Year: 1998
Tongue: English
Weight: 529 KB
Volume: 15
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1011954516233

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## Abstract Gene delivery from tissue engineering scaffolds can induce expression of tissue inductive factors to stimulate the cellular processes required for regeneration. Transfected cells secrete diffusible proteins that can create local concentration gradients, depending on the number, distribu