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How to screen non-viral gene delivery systems in vitro?

✍ Scribed by Ethlinn V.B. van Gaal; Roel van Eijk; Ronald S. Oosting; Robbert Jan Kok; Wim E. Hennink; Daan J.A. Crommelin; Enrico Mastrobattista


Book ID
113694660
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
828 KB
Volume
154
Category
Article
ISSN
0168-3659

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## Abstract Gene delivery from tissue engineering scaffolds can induce expression of tissue inductive factors to stimulate the cellular processes required for regeneration. Transfected cells secrete diffusible proteins that can create local concentration gradients, depending on the number, distribu