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In vitro metabolism of the anti-androgenic fungicide vinclozolin by rat liver microsomes

✍ Scribed by Adolfo Sierra-Santoyo; Esperanza Angeles-Soto; Ma. de Lourdes López-González; Randy A. Harrison; Michael F. Hughes

Book ID
105871062
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
437 KB
Volume
86
Category
Article
ISSN
0340-5761

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The metabolism of the tricyclic antidepressants amitriptyline (AMI), imipramine (IMI), chlorimipramine (CMI) and some of their metabolites was studied in vitro in isolated liver microsomes of female Spraque-Dawley rats. Nine metabolites of AMI, seven metabolites of IMI, and 11 metabolites of CMI wer