𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro metabolism of GV150013X by using liver microsomes and liver tissue slices from different species

✍ Scribed by M. Kajbaf; P. Rossato; L. Ferrari; P. Grossi; M. Pellegatti

Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
638 KB
Volume
22
Category
Article
ISSN
0378-7966

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

In Vitro metabolism of ciclesonide in hu
In Vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices
✍ Ruediger Nave; Robyn Fisher; Karl Zech πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 279 KB πŸ‘ 1 views

## Abstract Ciclesonide is a new‐generation inhaled corticosteroid developed to treat the inflammation associated with persistent asthma. In order to identify the properties of ciclesonide responsible for anti‐inflammatory activity, ciclesonide metabolism was investigated in human lung and liver pr

Assay of caffeine metabolism in vitro by
Assay of caffeine metabolism in vitro by human liver microsomes using radio-high-performance liquid chromatography
✍ F. Valero; R. De La Torre; A.R. Boobis; S. Murray; J. Segura πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 285 KB

The low turnover of caffeine in vitro by human liver microsomes makes the study of the metabolic pathways of this compound difficult. Analytical methods with high sensitivity and specificity are needed for the detection of its metabolic products. A method based on the on-line radiometric determinati

Metabolism of BW 1370U87 by crude liver
Metabolism of BW 1370U87 by crude liver homogenates from several species: An in vitro method for preliminary investigation of species differences in metabolism
✍ Mr. Ronald M. Norton; Helen L. White; Barrett R. Cooper πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 304 KB πŸ‘ 1 views

We employed broken cell liver preparations in order to investigate potential species-specific differences in the metabolism of BW 13701187, a new selective and reversible MAO-A inhibitor. The drug metabolizing capacity of crude liver homogenates from rat, dog, cat, monkey, and man was assessed based

Structural Investigations of 13-O-Demeth
Structural Investigations of 13-O-Demethyl-FK506 and Its Isomers Generated by in vitro Metabolism of FK506 Using Human-Liver Microsomes
✍ Wolfgang SchΓΌler; P. Schmieder; Horst Kessler; Uwe Christians; Ines Holze; Karl- πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 German βš– 775 KB

FK506 is currently under investigation as immunosuppressant after organ transplantation and in immune diseases. The structure of a demethylated metabolite 1 of FK506 isolated after in oitro metabolism by human-liver microsomes was established using two-dimensional homo-and heteronuclear NMR experime