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In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam

โœ Scribed by Jun Tang; K. Amin Usmani; Ernest Hodgson; Randy L. Rose

Book ID
113517040
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
154 KB
Volume
147
Category
Article
ISSN
0009-2797

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Inhibition of fipronil and nonane metabo
Inhibition of fipronil and nonane metabolism in human liver microsomes and human cytochrome P450 isoforms by chlorpyrifos
โœ Hyun Joo; Kyoungju Choi; Randy L. Rose; Ernest Hodgson ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 200 KB

## Abstract Previous studies have established that chlorpyrifos (CPS), fipronil, and nonane can all be metabolized by human liver microsomes (HLM) and a number of cytochrome P450 (CYP) isoforms. However, metabolic interactions between these three substrates have not been described. In this study th