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In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol

✍ Scribed by Khawja A. Usmani; Ernest Hodgson; Randy L. Rose

Book ID
113517089
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
436 KB
Volume
150
Category
Article
ISSN
0009-2797

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## Abstract Previous studies have established that chlorpyrifos (CPS), fipronil, and nonane can all be metabolized by human liver microsomes (HLM) and a number of cytochrome P450 (CYP) isoforms. However, metabolic interactions between these three substrates have not been described. In this study th