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In Vitro Conversion of Environmental Estrogenic Chemical Bisphenol A to DNA Binding Metabolite(s)

✍ Scribed by A. Atkinson; D. Roy


Book ID
115576608
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
505 KB
Volume
210
Category
Article
ISSN
0006-291X

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## Abstract Incubating dimethylaminoazobenzene [aniline ring (U)^14^ C] (DAB), purified thymus DNA and rat liver microsomes led to a covalent binding of radioactivity to DNA and proteins, which implied the presence of bound DAB metabolites. This binding required an enzymatic activation. We studied