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Effects of estrogens on aryl hydrocarbon hydroxylase mediated binding of benzo(a) pyrene metabolites to DNA in vitro

✍ Scribed by Marvin T. Williams; Robert Hendley

Book ID
118316241
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
385 KB
Volume
104
Category
Article
ISSN
0006-291X

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✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy