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Effects of harman and norharman on the mutagenicity and binding to DNA of benzo[a]pyrene metabolites in vitro and on aryl hydrocarbon hydroxylase induction in cell culture

โœ Scribed by Roy C. Levitt; Catherine Legraverend; Daniel W. Nebert; Olavi Pelkonen

Book ID
118311733
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
508 KB
Volume
79
Category
Article
ISSN
0006-291X

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## Abstract Primary cultures of human fetal oesophageal cells were set up and maintained for 45 days. Epithelial cells were the dominant cell type in the culture for the first four weeks. Thereafter, both epithelial cells and fibroblasts were seen with the fibroblasts becoming the dominant cell typ