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In vitro cell models to study nasal mucosal permeability and metabolism

✍ Scribed by M.Christiane Schmidt; Hagen Peter; Steffen R Lang; Günter Ditzinger; Hans P Merkle

Book ID
114176467
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
367 KB
Volume
29
Category
Article
ISSN
0169-409X

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The present work aims at the validation of excised bovine nasal mucosa as an in vitro model to address transport and metabolism pathways relative to the nasal mucosal uptake of therapeutic peptides. Preservation of the viability of the excised tissue in the course of in vitro studies of up to 3 h wa