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Nasal delivery of peptides: an in vitro cell culture model for the investigation of transport and metabolism in human nasal epithelium

✍ Scribed by Thomas Kissel; Ute Werner


Book ID
114163460
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
126 KB
Volume
53
Category
Article
ISSN
0168-3659

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The present work aims at the validation of excised bovine nasal mucosa as an in vitro model to address transport and metabolism pathways relative to the nasal mucosal uptake of therapeutic peptides. Preservation of the viability of the excised tissue in the course of in vitro studies of up to 3 h wa