𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro biocompatibility evaluation of surface-modified titanium alloys

✍ Scribed by Cristina Treves; Maria Martinesi; Maria Stio; Alejandro Gutiérrez; José Antonio Jiménez; María Francisca López

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
348 KB
Volume
9999A
Category
Article
ISSN
1549-3296

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The present work is aimed to evaluate the effects of a surface modification process on the biocompatibility of three vanadium‐free titanium alloys with biomedical applications interest. Chemical composition of alloys investigated, in weight %, were Ti‐7Nb‐6Al, Ti‐13Nb‐13Zr, and Ti‐15Zr‐4Nb. An easy and economic method intended to improve the biocompatibiblity of these materials consists in a simple thermal treatment at high temperature, 750°C, in air for different times. The significance of modification of the surface properties to the biological response was studied putting in contact both untreated and thermally treated alloys with human cells in culture, Human Umbilical Vein Endothelial Cells (HUVEC) and Human Peripheral Blood Mononuclear Cells (PBMC). The TNF‐α release data indicate that thermal treatment improves the biological response of the alloys. The notable enhancement of the surface roughness upon oxidation could be related with the observed reduction of the TNF‐α levels for treated alloys. A different behavior of the two cell lines may be observed, when adhesion molecules (ICAM‐1 and VCAM‐1 in HUVEC, ICAM‐1, and LFA‐1 in PBMC) were determined, PBMC being more sensitive than HUVEC to the contact with the samples. The data also distinguish surface composition and corrosion resistance as significant parameters for the biological response. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2010

📜 SIMILAR VOLUMES

The relation between electrochemical tes
The relation between electrochemical tests and in vitro evaluation of titanium alloy biocompatibility
✍ M. V. Popa; I. Demetrescu; D. Iordachescu; A. Cimpean; E. Vasilescu; P. Drob; C. 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 293 KB

## Abstract In this paper, the electrochemical behaviour of the titanium and Ti‐6Al‐7Nb alloy in artificial saliva (Tani&Zucchi and Carter–Brugirard), ion release tests and in vitro biocompatibility of human osteoblasts (HOB) were studied. Titanium and its implant Ti‐6Al‐7Nb alloy present self‐pass

Evaluation of the biocompatibility of ti
Evaluation of the biocompatibility of titanium-tantalum alloy versus titanium
✍ Prigent, H. ;Pellen-Mussi, P. ;Cathelineau, G. ;Bonnaure-Mallet, M. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB

To evaluate the biocompatibility of a new titanium-tantalum alloy, with qualities superior to titanium alone, for use in oral implantology, fibroblast and epithelial cell lines were grown on plastic, titanium, copper, and titanium-tantalum supports. Studies using scanning electron microscopy, flow c

Biocompatibility and hemocompatibility o
Biocompatibility and hemocompatibility of surface-modified NiTi alloys
✍ Armitage, David A. ;Parker, Terry L. ;Grant, David M. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB

## Abstract Nickel titanium (NiTi) shape memory alloys have been investigated for several years with regard to biomedical applications. However, little is known about the influences of surface modifications on the biocompatibility of these alloys. The effects of a range of surface treatments were i

In vitro biocompatibility assessment of
In vitro biocompatibility assessment of a nickel-titanium alloy using electron microscopyin situ end-labeling (EM-ISEL)
✍ Assad, M. ;Yahia, L. H. ;Rivard, C. H. ;Lemieux, N. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB

Shape memory nickel-titanium (NiTi) alloys are potential candidates for biomedical applications. However, their equiatomic composition (50 wt% Ni) is controversial, and concerns have been raised about their biocompatibility level because of the carcinogenicity potential. The relative in vitro genoto

In vitro biocompatibility assessment of
In vitro biocompatibility assessment of sulfonated polyrotaxane-immobilized polyurethane surfaces
✍ Park, Hyung Dal ;Lee, Won Kyu ;Ooya, Tooru ;Park, Ki Dong ;Kim, Young Ha ;Yui, N 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB

Sulfonated polyrotaxanes (PRx-SO(3)'s), in which sulfonated alpha-cyclodextrins (alpha-CDs) were threaded onto the poly(ethylene glycol) (PEG) segments in a PEG-b-poly(propylene glycol) (PPG)-b-PEG triblock copolymer (Pluronic) capped with benzyloxycarbonyl (Z)-L-phenylalanine (Z-L-Phe), were prepar