In vitro binding of retinoids to the nuclear retinoic acid receptor α
✍ Scribed by M.T. Cavey; B. Martin; I. Carlavan; B. Shroot
- Book ID
- 107714907
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 394 KB
- Volume
- 186
- Category
- Article
- ISSN
- 0003-2697
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Retinoids have been described to be potent modulators of cell proliferation, differentiation and apoptosis in various types of squamous-cell carcinoma (SCC) and myeloid cancer cells in vitro (Bollag and Holdener, 1992;Lotan et al., 1995). It has also been demonstrated that treatment of cells with re
These experiments were designed to test the ability of certain analogs and metabolites of all-transretinoic acid (RA), 13-cis-retinoic acid, 4-hydroxy-alltrans-retinoic acid, 4-keto-all-trans-retinoic acid, trimethylmethoxyphenol (TMMP) analog of retinoic acid, and TMMP analog of ethyl retinoate (et