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In vitro assessment of viral antigen content in inactivated aluminum hydroxide adjuvanted vaccines

โœ Scribed by Jonathan B. Katz; Steven K. Hanson; Peg A. Patterson; Ione R. Stoll


Book ID
118009982
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
589 KB
Volume
25
Category
Article
ISSN
0166-0934

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โœ Amber L. Clausi; Andrea Morin; John F. Carpenter; Theodore W. Randolph ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 228 KB

The mechanism(s) of the enhancement of the immune response by addition of aluminum salt adjuvants to parenterally administered protein-based vaccines is still the subject of debate. It has been hypothesized, however, that destabilization of the antigen structure on the surface of the adjuvant may be