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Effect of aluminum hydroxide adjuvant and formaldehyde in the formulation of rPA anthrax vaccine

✍ Scribed by S.F. Little; B.E. Ivins; W.M. Webster; S.L.W. Norris; G.P. Andrews

Book ID
116959510
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
150 KB
Volume
25
Category
Article
ISSN
0264-410X

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✍ Amber L. Clausi; Andrea Morin; John F. Carpenter; Theodore W. Randolph πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 228 KB

The mechanism(s) of the enhancement of the immune response by addition of aluminum salt adjuvants to parenterally administered protein-based vaccines is still the subject of debate. It has been hypothesized, however, that destabilization of the antigen structure on the surface of the adjuvant may be