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Assessment of the neurotoxic effects of aluminum hydroxide vaccine adjuvant injections in mice

✍ Scribed by Crépeaux, Guillemette; Heidi, Housam; David, Marie-Odile; Curmi, Patrick; Tzavara, Eleni; Giros, Bruno; Shaw, Christopher A.; Gherardi, Romain K.; Cadusseau, Josette

Book ID
127195690
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
65 KB
Volume
229
Category
Article
ISSN
0378-4274

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The mechanism(s) of the enhancement of the immune response by addition of aluminum salt adjuvants to parenterally administered protein-based vaccines is still the subject of debate. It has been hypothesized, however, that destabilization of the antigen structure on the surface of the adjuvant may be