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In vitro and in vivo transdermal iontophoretic delivery of naloxone, an opioid antagonist

โœ Scribed by Rie Yamamoto; Shinri Takasuga; Yoshimasa Yoshida; Shoichi Mafune; Katsuya Kominami; Chiyo Sutoh; Yukihiro Kato; Mitsugu Yamauchi; Masao Ito; Kiyoshi Kanamura; Mine Kinoshita


Book ID
113655671
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
446 KB
Volume
422
Category
Article
ISSN
0378-5173

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Transdermal iontophoretic delivery of tr
โœ Schuetz, Yannic B. (author);Naik, Aarti (author);Guy, Richard H. (author);Vuarid ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 124 KB

The feasibility of delivering triptorelin ]LHRH) by transdermal iontophoresis was evaluated in vitro. Peptide electrotransport at different current densities and donor concentrations was measured across porcine ear skin. The concomitant delivery of an electroosmotic marker enabled calculation of the